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The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore
Necrostatin (Nec-1) protects against ischemia-reperfusion (IR) injury in both brain and heart. We have previously reported in this journal that necrostatin can delay opening of the mitochondrial permeability transition pore (MPTP) in isolated cardiomyocytes. The aim of the present study was to inves...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874660/ https://ncbi.nlm.nih.gov/pubmed/17965927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-007-6067-6 |
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