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The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore

Necrostatin (Nec-1) protects against ischemia-reperfusion (IR) injury in both brain and heart. We have previously reported in this journal that necrostatin can delay opening of the mitochondrial permeability transition pore (MPTP) in isolated cardiomyocytes. The aim of the present study was to inves...

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Detalhes bibliográficos
Main Authors: Lim, SY, Davidson, SM, Mocanu, MM, Yellon, DM, Smith, CCT
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874660/
https://ncbi.nlm.nih.gov/pubmed/17965927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-007-6067-6
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