Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro

The nuclear receptor farnesoid X receptor alpha (FXRα, NR1H4) is activated by bile acids in multiple species including mouse, rat, and human and in this study we have identified two isoforms of Fxrα in Japanese medaka (Oryzias latipes), a small freshwater teleost. Both isoforms share a high amino ac...

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Hoofdauteurs: Howarth, Deanna L., Hagey, Lee R., Law, Sheran H.W., Ai, Ni, Krasowski, Matthew D., Ekins, Sean, Moore, John T., Kollitz, Erin M., Hinton, David E., Kullman, Seth W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874645/
https://ncbi.nlm.nih.gov/pubmed/20430454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2010.02.020
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