Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro

The nuclear receptor farnesoid X receptor alpha (FXRα, NR1H4) is activated by bile acids in multiple species including mouse, rat, and human and in this study we have identified two isoforms of Fxrα in Japanese medaka (Oryzias latipes), a small freshwater teleost. Both isoforms share a high amino ac...

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Detalhes bibliográficos
Main Authors: Howarth, Deanna L., Hagey, Lee R., Law, Sheran H.W., Ai, Ni, Krasowski, Matthew D., Ekins, Sean, Moore, John T., Kollitz, Erin M., Hinton, David E., Kullman, Seth W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874645/
https://ncbi.nlm.nih.gov/pubmed/20430454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2010.02.020
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