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Mechanisms involved in the Enhancement of Mammalian Target of Rapamycin Signalling and Hypertrophy in Skeletal Muscle of Myostatin-deficient Mice

Myostatin deficiency leads to both an increased rate of protein synthesis and skeletal muscle hypertrophy. However, the mechanisms involved in mediating these effects are not yet fully understood. Here, we demonstrate that genetic loss of myostatin leads to enhanced muscle expression of both PKB and...

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Detalhes bibliográficos
Main Authors: Lipina, Christopher, Kendall, Hannah, McPherron, Alexandra C, Taylor, Peter M, Hundal, Harinder S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874630/
https://ncbi.nlm.nih.gov/pubmed/20412806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.04.039
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