IL-22 producing “T22” T-cells account for up-regulated IL-22 in atopic dermatitis (AD), despite reduced IL-17 producing Th17 T-cells

BACKGROUND: Psoriasis and atopic dermatitis (AD) are common inflammatory skin diseases. Up-regulated Th17/IL-23 pathway was demonstrated in psoriasis. Although potential involvement of Th17 T-cells in AD was suggested during acute disease, the role of these cells in chronic AD remains unclear. OBJEC...

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Autori principali: Nograles, Kristine E., Zaba, Lisa C., Shemer, Avner, Fuentes-Duculan, Judilyn, Cardinale, Irma, Kikuchi, Toyoko, Ramon, Michal, Bergman, Reuven, Krueger, James G., Guttman-Yassky, Emma
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874584/
https://ncbi.nlm.nih.gov/pubmed/19439349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.03.041
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