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Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not “immediate-response” TNF genes

BACKGROUND: TNF inhibitors have revolutionized the treatment of psoriasis vulgaris, as well as psoriatic and rheumatoid arthritis, and Crohns disease. Despite our understanding that these agents block TNF, their complex mechanism of action in disease resolution is still unclear. OBJECTIVE: To global...

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Dettagli Bibliografici
Autori principali: Zaba, Lisa C., Suárez-Fariñas, Mayte, Fuentes-Duculan, Judilyn, Nograles, Kristine, Guttman-Yassky, Emma, Cardinale, Irma, Lowes, Michelle A., Krueger, James G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852188/
https://ncbi.nlm.nih.gov/pubmed/19895991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.08.046
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