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Promoter Demethylation and Chromatin Remodeling by Green Tea Polyphenols Leads to Re-expression of GSTP1 in Human Prostate Cancer Cells

Epigenetic silencing of gluthathione-S-transferase pi (GSTP1) is recognized as being a molecular hallmark of human prostate cancer. We investigated the effects of green tea polyphenols (GTP) on GSTP1 re-expression and further elucidated its mechanism of action and long-term safety, compared with nuc...

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Autori principali: Pandey, Mitali, Shukla, Sanjeev, Gupta, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874465/
https://ncbi.nlm.nih.gov/pubmed/19856314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24988
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