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Promoter Demethylation and Chromatin Remodeling by Green Tea Polyphenols Leads to Re-expression of GSTP1 in Human Prostate Cancer Cells
Epigenetic silencing of gluthathione-S-transferase pi (GSTP1) is recognized as being a molecular hallmark of human prostate cancer. We investigated the effects of green tea polyphenols (GTP) on GSTP1 re-expression and further elucidated its mechanism of action and long-term safety, compared with nuc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874465/ https://ncbi.nlm.nih.gov/pubmed/19856314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24988 |
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