Inhibition of K+ efflux and dehydration of sickle cells by [(dihydroindenyl)oxy]alkanoic acid: an inhibitor of the K+ Cl- cotransport system.

[(Dihydroindenyl)oxy]alkanoic acid (DIOA) was recently introduced as a potent inhibitor of the K+Cl- cotransport system without side effects on other cation transport systems [Garay, R. P., Nazaret, C., Hannaert, P.A. & Cragoe, E. J., Jr. (1988) Mol. Pharmacol. 33, 696-701]. In sickle cells, an...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Vitoux, D, Olivieri, O, Garay, R P, Cragoe, E J, Galacteros, F, Beuzard, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1989
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.11.4273
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