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Differential oxygen sensitivity of the K(+)-Cl(−) cotransporter in normal and sickle human red blood cells

1. K(+) influx and efflux were measured in normal (HbA) and sickle (HbS) red blood cells to investigate the interaction of swelling, H(+) ions and urea with O(2) (0 to 150 mmHg O(2)) in the presence of ouabain and bumetanide (both 100 μM). 2. In HbA cells, K(+)-Cl(−) cotransport was O(2) dependent....

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Main Authors: Gibson, J S, Speake, P F, Ellory, J C
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231113/
https://ncbi.nlm.nih.gov/pubmed/9679176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.225bi.x
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