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Colloid Formation by Drugs in Simulated Intestinal Fluid
[Image: see text] Many organic molecules form colloidal aggregates in aqueous solution at micromolar concentrations. These aggregates promiscuously inhibit soluble proteins and are a major source of false positives in high-throughput screening. Several drugs also form colloidal aggregates, and there...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2010
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874266/ https://ncbi.nlm.nih.gov/pubmed/20426472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100254w |
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