The Effect of Neighboring Methionine Residue on Tyrosine Nitration & Oxidation in Peptides Treated with MPO, H(2)O(2), & NO(2)(-) or Peroxynitrite and Bicarbonate: Role of Intramolecular Electron-Transfer Mechanism?

Recent reports suggest that intramolecular electron-transfer reactions can profoundly affect the site and specificity of tyrosyl nitration and oxidation in peptides and proteins. Here we investigated the effects of methionine on tyrosyl nitration and oxidation induced by myeloperoxidase (MPO), H(2)O...

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Detalhes bibliográficos
Main Authors: Zhang, Hao, Zielonka, Jacek, Sikora, Adam, Joseph, Joy, Xu, Yingkai, Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874256/
https://ncbi.nlm.nih.gov/pubmed/19056332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.11.018
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