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The Effect of Neighboring Methionine Residue on Tyrosine Nitration & Oxidation in Peptides Treated with MPO, H(2)O(2), & NO(2)(-) or Peroxynitrite and Bicarbonate: Role of Intramolecular Electron-Transfer Mechanism?

Recent reports suggest that intramolecular electron-transfer reactions can profoundly affect the site and specificity of tyrosyl nitration and oxidation in peptides and proteins. Here we investigated the effects of methionine on tyrosyl nitration and oxidation induced by myeloperoxidase (MPO), H(2)O...

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Détails bibliographiques
Auteurs principaux: Zhang, Hao, Zielonka, Jacek, Sikora, Adam, Joseph, Joy, Xu, Yingkai, Kalyanaraman, B.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874256/
https://ncbi.nlm.nih.gov/pubmed/19056332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.11.018
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