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Monitoring Therapeutic Efficacy by Real-Time Mycobacterium tuberculosis mRNA Detection in Sputum

BACKGROUND: Current laboratory methods for monitoring response to therapy for tuberculosis (TB) rely on mycobacterial culture. Their clinical usefulness is therefore limited by the slow growth rate of Mycobacterium tuberculosis. Rapid methods to reliably quantify response to anti-TB drug efficacy ar...

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Detalhes bibliográficos
Main Authors: Mdivani, Nino, Li, Haijing, Akhalaia, Maka, Gegia, Medea, Goginashvili, Leila, Kernodle, Douglas S., Khechinashvili, George, Tang, Yi-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874158/
https://ncbi.nlm.nih.gov/pubmed/19574468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2009.124396
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