Sputum Mycobacterium tuberculosis mRNA as a Marker of Bacteriologic Clearance in Response to Antituberculosis Therapy

mRNA is a marker of cell viability. Quantifying Mycobacterium tuberculosis mRNA in sputum is a promising tool for monitoring response to antituberculosis therapy and evaluating the efficacy of individual drugs. mRNA levels were measured in sputum specimens from patients with tuberculosis (TB) receiv...

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Autors principals: Li, L., Mahan, C. S., Palaci, M., Horter, L., Loeffelholz, L., Johnson, J. L., Dietze, R., Debanne, S. M., Joloba, M. L., Okwera, A., Boom, W. H., Eisenach, K. D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812283/
https://ncbi.nlm.nih.gov/pubmed/19923475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01526-09
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