Prevalence of and Molecular Basis for Tuberculosis Drug Resistance in the Republic of Georgia: Validation of a QIAplex System for Detection of Drug Resistance-Related Mutations

We developed a QIAplex system for the simultaneous detection of 24 Mycobacterium tuberculosis gene mutations responsible for resistance to isoniazid (INH), rifampin (RIF), streptomycin (STM), and ethambutol (EMB) in 196 M. tuberculosis isolates recovered in the Republic of Georgia. In comparison to...

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Detalhes bibliográficos
Main Authors: Gegia, Medea, Mdivani, Nino, Mendes, Rodrigo E., Li, Haijing, Akhalaia, Maka, Han, Jian, Khechinashvili, George, Tang, Yi-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224719/
https://ncbi.nlm.nih.gov/pubmed/18070968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01124-07
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