CD4(+) T CELLS ELICIT HOST IMMUNE RESPONSES TO MHC-II(−) OVARIAN CANCER THROUGH CCL5 SECRETION AND CD40-MEDIATED LICENSING OF DENDRITIC CELLS

T cell adoptive transfer strategies that have produced clinical remissions against specific tumors have so far produced disappointing results against ovarian cancer. Recent evidence suggests that adoptively transferred CD4(+) T cells can trigger endogenous immune responses in particular ovarian canc...

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Main Authors: Nesbeth, Yolanda C., Martinez, Diana G., Toraya, Seiko, Scarlett, Uciane K., Cubillos-Ruiz, Juan R., Rutkowski, Melanie R., Conejo-Garcia, Jose R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874073/
https://ncbi.nlm.nih.gov/pubmed/20400704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903247
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