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Functional Significance May Underlie the Taxonomic Utility of Single Amino Acid Substitutions in Conserved Proteins
We hypothesized that some amino acid substitutions in conserved proteins that are strongly fixed by critical functional roles would show lineage-specific distributions. As an example of an archetypal conserved eukaryotic protein we considered the active site of β-tubulin. Our analysis identified one...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874023/ https://ncbi.nlm.nih.gov/pubmed/20386893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-010-9338-y |
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