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A Single Amino Acid Substitution in HIV-1 Reverse Transcriptase Significantly Reduces Virion Release
HIV-1 protease (PR) mediates the proteolytic processing of virus particles during or after virus budding. PR activation is thought to be triggered by appropriate Gag-Pol/Gag-Pol interaction; factors affecting this interaction either enhance or reduce PR-mediated cleavage efficiency, resulting in mar...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798345/ https://ncbi.nlm.nih.gov/pubmed/19889767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01532-09 |
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