Toll-Like Receptor 4 Promoter Polymorphisms: Common TLR4 Variants May Protect against Severe Urinary Tract Infection

BACKGROUND: Polymorphisms affecting Toll-like receptor (TLR) structure appear to be rare, as would be expected due to their essential coordinator role in innate immunity. Here, we assess variation in TLR4 expression, rather than structure, as a mechanism to diversify innate immune responses. METHODO...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ragnarsdóttir, Bryndís, Jönsson, Klas, Urbano, Alexander, Grönberg-Hernandez, Jenny, Lutay, Nataliya, Tammi, Martti, Gustafsson, Mattias, Lundstedt, Ann-Charlotte, Leijonhufvud, Irene, Karpman, Diana, Wullt, Björn, Truedsson, Lennart, Jodal, Ulf, Andersson, Björn, Svanborg, Catharina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873976/
https://ncbi.nlm.nih.gov/pubmed/20505764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010734
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