Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility

BACKGROUND: Protein kinase D (PKD) has been implicated in a wide range of cellular processes and pathological conditions including cancer. However, targeting PKD therapeutically and dissecting PKD-mediated cellular responses remains difficult due to lack of a potent and selective inhibitor. Previous...

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Detalhes bibliográficos
Main Authors: LaValle, Courtney R, Bravo-Altamirano, Karla, Giridhar, Karthik V, Chen, Jun, Sharlow, Elizabeth, Lazo, John S, Wipf, Peter, Wang, Q Jane
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873968/
https://ncbi.nlm.nih.gov/pubmed/20444281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-10-5
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