Potent and Selective Disruption of Protein Kinase D Functionality by a Benzoxoloazepinolone

Protein kinase D (PKD) is a novel family of serine/threonine kinases targeted by the second messenger diacylglycerol. It has been implicated in many important cellular processes and pathological conditions. However, further analysis of PKD in these processes is severely hampered by the lack of a PKD...

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Detalhes bibliográficos
Main Authors: Sharlow, Elizabeth R., Giridhar, Karthik V., LaValle, Courtney R., Chen, Jun, Leimgruber, Stephanie, Barrett, Rebecca, Bravo-Altamirano, Karla, Wipf, Peter, Lazo, John S., Wang, Q. Jane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586241/
https://ncbi.nlm.nih.gov/pubmed/18829454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805358200
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