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Inducible silencing of protein kinase D3 inhibits secretion of tumor-promoting factors in prostate cancer

Protein kinase D acts as a major mediator of several signaling pathways related to cancer development. Aberrant PKD expression and activity have been demonstrated in multiple cancers, and novel PKD inhibitors show promising anti-cancer activities. Despite these advances, the mechanisms through which...

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Main Authors: LaValle, Courtney R., Zhang, Liyong, Xu, Shuping, Eiseman, Julie L., Wang, Q. Jane
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392457/
https://ncbi.nlm.nih.gov/pubmed/22532599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0887
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