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Gold(I) phosphine mediated selective inhibition of lymphoid tyrosine phosphatase

Selective protein tyrosine phosphatase (PTP) inhibition is often difficult to achieve owing to the high degree of similarity of the catalytic domains of this family of enzymes. Selective inhibitors of the lymphoid specific tyrosine phosphatase, LYP, are of great interest due to the involvement of LY...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karver, Mark R., Krishnamurthy, Divya, Bottini, Nunzio, Barrios, Amy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873867/
https://ncbi.nlm.nih.gov/pubmed/20083307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2009.12.012
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