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Targeting a Ruthenium Complex to the Nucleus with Short Peptides

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine has been found to improve both the uptake and nuclear localization efficiency of these complexes,...

詳細記述

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書誌詳細
主要な著者: Puckett, Cindy A., Barton, Jacqueline K.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873839/
https://ncbi.nlm.nih.gov/pubmed/20430627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.081
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