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Targeting a Ruthenium Complex to the Nucleus with Short Peptides

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine has been found to improve both the uptake and nuclear localization efficiency of these complexes,...

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Detaylı Bibliyografya
Asıl Yazarlar: Puckett, Cindy A., Barton, Jacqueline K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873839/
https://ncbi.nlm.nih.gov/pubmed/20430627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.081
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