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Targeting a Ruthenium Complex to the Nucleus with Short Peptides
In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine has been found to improve both the uptake and nuclear localization efficiency of these complexes,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873839/ https://ncbi.nlm.nih.gov/pubmed/20430627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.081 |
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