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Targeting a Ruthenium Complex to the Nucleus with Short Peptides

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine has been found to improve both the uptake and nuclear localization efficiency of these complexes,...

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Autors principals: Puckett, Cindy A., Barton, Jacqueline K.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873839/
https://ncbi.nlm.nih.gov/pubmed/20430627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.081
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