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Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study

BACKGROUND: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key mechanism in this technique is to design efficient siRNAs that incorporated into the RNA-induced silencing complexes (RI...

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Hlavní autoři: Liu, Qi, Xu, Qian, Zheng, Vincent W, Xue, Hong, Cao, Zhiwei, Yang, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873531/
https://ncbi.nlm.nih.gov/pubmed/20380733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-181
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