Signal pathways JNK and NF-κB, identified by global gene expression profiling, are involved in regulation of TNFα-induced mPGES-1 and COX-2 expression in gingival fibroblasts

BACKGROUND: Prostaglandin E(2 )(PGE(2)) is involved in several chronic inflammatory diseases including periodontitis, which causes loss of the gingival tissue and alveolar bone supporting the teeth. We have previously shown that tumor necrosis factor α (TNFα) induces PGE(2 )synthesis in gingival fib...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Båge, Tove, Lindberg, Johan, Lundeberg, Joakim, Modéer, Thomas, Yucel-Lindberg, Tülay
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873473/
https://ncbi.nlm.nih.gov/pubmed/20398340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-241
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