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Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells
BACKGROUND: The class 1 carcinogen cadmium (Cd(2+)) disrupts the E-cadherin/β-catenin complex of epithelial adherens junctions (AJs) and causes renal cancer. Deregulation of E-cadherin adhesion and changes in Wnt/β-catenin signaling are known to contribute to carcinogenesis. RESULTS: We investigated...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873433/ https://ncbi.nlm.nih.gov/pubmed/20459685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-102 |
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