Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.

Human follicular B-cell lymphomas possess a t(14;18) that translocates a putative protooncogene, BCL2, into the immunoglobulin heavy chain locus. The normal BCL2 gene is quiescent in resting B cells, expressed in proliferating, but down-regulated in differentiated B cells. Inappropriately high level...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Nunez, G, Seto, M, Seremetis, S, Ferrero, D, Grignani, F, Korsmeyer, S J, Dalla-Favera, R
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4589
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