Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.

Human follicular B-cell lymphomas possess a t(14;18) that translocates a putative protooncogene, BCL2, into the immunoglobulin heavy chain locus. The normal BCL2 gene is quiescent in resting B cells, expressed in proliferating, but down-regulated in differentiated B cells. Inappropriately high level...

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Hlavní autoři: Nunez, G, Seto, M, Seremetis, S, Ferrero, D, Grignani, F, Korsmeyer, S J, Dalla-Favera, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1989
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC287316/
https://ncbi.nlm.nih.gov/pubmed/2543982
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