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Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.
Human follicular B-cell lymphomas possess a t(14;18) that translocates a putative protooncogene, BCL2, into the immunoglobulin heavy chain locus. The normal BCL2 gene is quiescent in resting B cells, expressed in proliferating, but down-regulated in differentiated B cells. Inappropriately high level...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1989
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4589 |
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