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PI3K/Akt and mTOR/p70S6K Pathways Mediate Neuroprotectin D1-Induced Retinal Pigment Epithelial Cell Survival during Oxidative Stress-Induced Apoptosis

The initiation and progression of several forms of retinal degenerations involve excessive, repetitive, and/or sustained oxidative stress that, in turn, mediate photoreceptor cell damage and death. Since phosphatidylinositol 3-kinase (PI3K)/Akt and mTOR/p70S6-kinase pathways are part of survival sig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Faghiri, Zahra, Bazan, Nicolas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873108/
https://ncbi.nlm.nih.gov/pubmed/20230819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.03.002
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