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PI3K/AKT/mTOR signaling pathway inhibitors in proliferation of retinal pigment epithelial cells

AIM: To determine whether the PI3K/AKT/mTOR pathway is activated in proliferative vitreoretinopathy (PVR) in homo-sapiens. METHODS: The retina of controls and patients with PVR were collected and their levels of PI3K, phospho-AKT, phospho-mTOR, phospho-p70S6k and phospho-4EBP-1 were determined by We...

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Detalhes bibliográficos
Main Authors: Cai, Na, Dai, Shun-Dong, Liu, Ning-Ning, Liu, Li-Min, Zhao, Ning, Chen, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530807/
https://ncbi.nlm.nih.gov/pubmed/23275900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2012.06.05
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