Evidence of Receptor-Mediated Elimination of Erythropoietin by Analysis of Erythropoietin Receptor mRNA Expression in Bone Marrow and Erythropoietin Clearance During Anemia

Erythropoietin (Epo) is the primary hormone that stimulates erythroid proliferation and differentiation through its cell surface receptor (EpoR) on erythroid progenitor cells. Previous studies have suggested that the bone marrow plays an important role in Epo's elimination. The changes in the E...

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Bibliographic Details
Main Authors:	Nalbant, Demet, Saleh, Mohammad, Goldman, Frederic D., Widness, John A., Veng-Pedersen, Peter
Format:	Artigo
Language:	Inglês
Published:	The American Society for Pharmacology and Experimental Therapeutics 2010
Subjects:	Metabolism, Transport, and Pharmacogenomics
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2872962/ https://ncbi.nlm.nih.gov/pubmed/20103588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163568
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Evidence of Receptor-Mediated Elimination of Erythropoietin by Analysis of Erythropoietin Receptor mRNA Expression in Bone Marrow and Erythropoietin Clearance During Anemia

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