Evidence of Receptor-Mediated Elimination of Erythropoietin by Analysis of Erythropoietin Receptor mRNA Expression in Bone Marrow and Erythropoietin Clearance During Anemia

Erythropoietin (Epo) is the primary hormone that stimulates erythroid proliferation and differentiation through its cell surface receptor (EpoR) on erythroid progenitor cells. Previous studies have suggested that the bone marrow plays an important role in Epo's elimination. The changes in the E...

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Autori principali: Nalbant, Demet, Saleh, Mohammad, Goldman, Frederic D., Widness, John A., Veng-Pedersen, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
Soggetti:
Metabolism, Transport, and Pharmacogenomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872962/
https://ncbi.nlm.nih.gov/pubmed/20103588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163568
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