Evidence of Receptor-Mediated Elimination of Erythropoietin by Analysis of Erythropoietin Receptor mRNA Expression in Bone Marrow and Erythropoietin Clearance During Anemia

Erythropoietin (Epo) is the primary hormone that stimulates erythroid proliferation and differentiation through its cell surface receptor (EpoR) on erythroid progenitor cells. Previous studies have suggested that the bone marrow plays an important role in Epo's elimination. The changes in the E...

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Main Authors: Nalbant, Demet, Saleh, Mohammad, Goldman, Frederic D., Widness, John A., Veng-Pedersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Metabolism, Transport, and Pharmacogenomics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872962/
https://ncbi.nlm.nih.gov/pubmed/20103588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163568
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