Metabolism of 17α-Hydroxyprogesterone Caproate, an Agent for Preventing Preterm Birth, by Fetal Hepatocytes

Preterm delivery (i.e., delivery before 37 completed weeks of gestation) is a major determinant of neonatal morbidity and mortality. Until recently, no effective therapies for prevention of preterm birth existed. In a recent multicentered trial, 17α-hydroxyprogesterone caproate (17-OHPC) was shown t...

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Autori principali: Sharma, Shringi, Ellis, Ewa C. S., Dorko, Kenneth, Zhang, Shimin, Mattison, Donald R., Caritis, Steve N., Venkataramanan, Raman, Strom, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
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Short Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872946/
https://ncbi.nlm.nih.gov/pubmed/20097724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.029918
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