Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

The Cdc42 guanosine triphosphatase is essential for cell polarization in several organisms and in vitro for the organization of polarized epithelial cysts. A long-standing question concerns the identity of the guanine nucleotide exchange factor (GEF) that controls this process. Using Madin–Darby can...

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Bibliographic Details
Main Authors: Qin, Yi, Meisen, Walter H., Hao, Yi, Macara, Ian G.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872902/
https://ncbi.nlm.nih.gov/pubmed/20479467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002097
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