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Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

The Cdc42 guanosine triphosphatase is essential for cell polarization in several organisms and in vitro for the organization of polarized epithelial cysts. A long-standing question concerns the identity of the guanine nucleotide exchange factor (GEF) that controls this process. Using Madin–Darby can...

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Autores principales: Qin, Yi, Meisen, Walter H., Hao, Yi, Macara, Ian G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872902/
https://ncbi.nlm.nih.gov/pubmed/20479467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002097
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