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Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

Osteoblast-specific expression of the bone protein osteocalcin is controlled at the transcriptional level by the steroid hormone 1 alpha,25-dihydroxyvitamin D3. As this protein may represent a marker for bone activity in human disease, we examined the regulation of its expression at the molecular le...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kerner, S A, Scott, R A, Pike, J W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2786632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4455
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