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Wnt4 and LAP2alpha as Pacemakers of Thymic Epithelial Senescence
Age-associated thymic involution has considerable physiological impact by inhibiting de novo T-cell selection. This impaired T-cell production leads to weakened immune responses. Yet the molecular mechanisms of thymic stromal adipose involution are not clear. Age-related alterations also occur in th...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
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Public Library of Science
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872673/ https://ncbi.nlm.nih.gov/pubmed/20502698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010701 |
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