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Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence
Members of the Wnt family of secreted glyco-lipo-proteins affect intrathymic T-cell development and are abundantly secreted by thymic epithelial cells (TECs) that create the specific microenvironment for thymocytes to develop into mature T-cells. During ageing, Wnt expression declines allowing adipo...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Ireland
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146701/ https://ncbi.nlm.nih.gov/pubmed/21549744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.04.007 |
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