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PPARgamma Deficiency Counteracts Thymic Senescence

Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As with other adipose tissues, thymic adipose involution is also controlled by PPARgamma. This is supported by observations reporting that systemic...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Ernszt, David, Banfai, Krisztina, Kellermayer, Zoltan, Pap, Attila, Lord, Janet M., Pongracz, Judit E., Kvell, Krisztian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681731/
https://ncbi.nlm.nih.gov/pubmed/29163553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01515
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