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Target mRNA abundance dilutes microRNA and siRNA activity
Post-transcriptional regulation by microRNAs and siRNAs depends not only on characteristics of individual binding sites in target mRNA molecules, but also on system-level properties such as overall molecular concentrations. We hypothesize that an intracellular pool of microRNAs/siRNAs faced with a l...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872614/ https://ncbi.nlm.nih.gov/pubmed/20404830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.24 |
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