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Mechanisms of tau-induced neurodegeneration

Alzheimer disease (AD) and related tauopathies are histopathologically characterized by a specific type of slow and progressive neurodegeneration, which involves the abnormal hyperphosphorylation of the microtubule associated protein (MAP) tau. This hallmark, called neurofibrillary degeneration, is...

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Detalhes bibliográficos
Main Authors: Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin, Alonso, Alejandra del C., Grundke-Iqbal, Inge
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872491/
https://ncbi.nlm.nih.gov/pubmed/19184068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-009-0486-3
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