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Mechanisms of tau-induced neurodegeneration
Alzheimer disease (AD) and related tauopathies are histopathologically characterized by a specific type of slow and progressive neurodegeneration, which involves the abnormal hyperphosphorylation of the microtubule associated protein (MAP) tau. This hallmark, called neurofibrillary degeneration, is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872491/ https://ncbi.nlm.nih.gov/pubmed/19184068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-009-0486-3 |
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