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Plk4 is required for cytokinesis and maintenance of chromosomal stability

Aneuploidy is a characteristic feature of established cancers and can promote tumor development. Aneuploidy may arise directly, through unequal distribution of chromosomes into daughter cells, or indirectly, through a tetraploid intermediate. The polo family kinase Plk4/Sak is required for late mito...

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מידע ביבליוגרפי
Main Authors: Rosario, Carla O., Ko, Michael A., Haffani, Yosr Z., Gladdy, Rebecca A., Paderova, Jana, Pollett, Aaron, Squire, Jeremy A., Dennis, James W., Swallow, Carol J.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872425/
https://ncbi.nlm.nih.gov/pubmed/20348415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910941107
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