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Plk4 is required for cytokinesis and maintenance of chromosomal stability
Aneuploidy is a characteristic feature of established cancers and can promote tumor development. Aneuploidy may arise directly, through unequal distribution of chromosomes into daughter cells, or indirectly, through a tetraploid intermediate. The polo family kinase Plk4/Sak is required for late mito...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872425/ https://ncbi.nlm.nih.gov/pubmed/20348415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910941107 |
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